Anti-Epilepsy Drugs Lose Effectiveness Over Time…

Epilepsy Talk

It may be the dose prescribed…the type of epilepsy you have…even something as simple as your age or weight. But research shows that, over time, the effectiveness of your anti-epilepsy drug may decline.

Almost all first, second and third-generation epilepsy drugs lose their efficacy after prolonged treatment.

Perhaps it’s because your metabolism builds up a tolerance to the drug. And ramping up the dosage can work.

Or it may be a functional tolerance where your brain receptors have become resistant to the drug. In that case, a change in medications may help. But whatever the cause, you’re not alone…

Patients showing tolerance to traditional drugs

A critical review by Dr. Wolfgang Loscher and Dr. Dieter Schmidt shows that repeated administration of anti-epileptic drug (AED) therapy has diminishing results in preventing seizures in epileptic patients.

In clinical trials, the number of patients remaining seizure-free declines over time with prolonged treatment.

This review explores…

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Epilepsy Related Conditions

Epilepsy Talk

In chronic conditions, such as epilepsy, the coexistence of more than one illness in a patient is the rule rather than the exception…

Men and women with epilepsy have a two-to five-fold increase in the occurrence of conditions, such as migraine, cerebrovascular and cardiovascular disorders, along with gastrointestinal disorders, pulmonary disorders, dementia, chronic fatigue, mood disorders, anxiety, and personality disorders.

The type and prevalence of conditions is largely age dependent.  For example, among epilepsy patients, asthma is common among the young, while cardiovascular diseases and stroke are prevalent in older individuals—but both occur more frequently than in the general population.

Below is a sampling of some of the conditions which are related (but not necessarily caused) by epilepsy…

Epilepsy and Heart Disease

The neural activity that accompanies seizures has long been known to affect cardiac functioning. But in patients with nonconvulsive types of epilepsy, these secondary symptoms may be…

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New Hope for Epilepsy Stem Cell Therapy

Epilepsy Talk

About stem cells: “They’ve been called magic seeds. They have the potential to cure disease, regenerate organs, and even prolong life. And they could completely alter the way we practice medicine”  Fortune Magazine

There are many exciting areas in epilepsy research. One topic of great interest is the use of stem cells to treat seizures.

Cell transplants have become a recent focus in epilepsy research, due to a lack of effective treatments, according to Scott C. Baraban, PhD.

Baraban says that current drugs are focused on treating symptoms as opposed to the cause and fail to provide therapeutic benefit in many forms of epilepsy.

Although stem cell research related to epilepsy is in its early stages, preliminary data suggests promise for this treatment option.

Here’s how it works:

When an organism (a human, mouse, etc) is developing, the organism will start as a single fertilized cell. This cell will begin dividing.

Stem cells are…

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Help Line

Epilepsy Talk

The secret here is the numbers 211.

Go to the website:http://www.211.org/. Where available, 211 allows people to give help and to get help. 

211 can also give people who live in rural areas better access to health and human service information.

Simply dial 211 from any telephone and you will reach the Information and Referral service or the United Way for your state.

The 211 center’s referral specialists question callers, access databases of resources available from private and public health and human service agencies, match the callers’ needs to available resources, and link or refer them directly to an agency or organization that can help.

Types of Referrals Offered by 211 — Provides callers with information about and referrals to social services for every-day needs and in times of crisis. For example, 211 can offer access to the following types of services:

Basic Human Needs Resources – including food and…

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Taking a Knee?

northierthanthou

Institute of American Indian Arts (Photo compliments of Moni)

Not everyone really appreciates just how powerful the ritual of standing for the National Anthem really can be. I got a real sense of this when I was 14. My Jr. rifle team won the Wyoming-state BB-Gun finals, which earned our way to the International BB-Gun Championship in Bowling Green, Kentucky. …on July 4th. As the child of a career military officer, I was always happy to stand for the Star-Spangled Banner or to recite the Pledge of Allegiance, but standing there during the final ceremonies, the whole thing took on a whole new layer of meaning for me. That time, I had my heart in my throat. That time, the whole ritual moved me nearly to tears. I loved my country so much, and at that moment, putting my hand over my heart for that beautiful song was absolutely the…

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This 19th century lady doctor helped usher Indian women into medicine

via This 19th century lady doctor helped usher Indian women into medicine

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